Description
Exploring 5C-AKB48: A Synthetic Cannabinoid of Concern
Buy 5CAKB48 Powder, a synthetic cannabinoid, has garnered attention in the realm of research chemicals. Structurally related to AKB48, it is distinguished by the addition of a chlorine atom at the 5-position of the indazole ring. This modification enhances its potency and affinity for cannabinoid receptors, particularly CB1 and CB2.
Chemical Profile and Potency
The molecular structure of 5C-AKB48 contributes to its high binding affinity to cannabinoid receptors. This affinity translates to potent psychoactive effects, making it a subject of interest in pharmacological studies. However, this potency also raises concerns regarding its safety and potential for abuse.
Pharmacological Effects
In vivo studies have demonstrated that 5C-AKB48 induces a range of effects in animal models. These include hypothermia, increased pain thresholds, catalepsy, and reduced motor activity. Additionally, it impairs sensorimotor responses and can lead to seizures and hyperreflexia. These effects are consistent with those observed in other synthetic cannabinoids, indicating a significant impact on the central nervous system.
Toxicity and Cytotoxicity
Research has highlighted the cytotoxic potential of 5C-AKB48. Studies indicate that the presence of damiana plant material can enhance the cytotoxicity of 5C-AKB48, suggesting that its use in herbal blends may increase health risks. This underscores the importance of considering the composition of substances containing synthetic cannabinoids.
Legal Status and Research Use
The legal status of 5C-AKB48 varies by jurisdiction. In many regions, it is classified as a controlled substance due to its psychoactive properties and potential for abuse. However, it is available in certain markets for research purposes, where it is used to study the effects of synthetic cannabinoids on the endocannabinoid system.
Buy 5CAKB48 Powder, is a potent synthetic cannabinoid with significant pharmacological effects. While it serves as a valuable tool in research settings, its potential for abuse and associated health risks necessitate caution. Further studies are essential to fully understand its impact and to inform regulatory decisions regarding its use and distribution.
Key Chemical Information:
- IUPAC Name: N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-chloropentyl)-1H-indazole-3-carboxamide
- Synonyms: 5-chloro AB-KB48, 5CAKB48
- Molecular Formula: C20H28ClN3O2
- Molar Mass: 377.91 g/mol
- CAS Number: Available upon request
- Purity: ≥99% (HPLC verified)
- Form: White crystalline powder
- Solubility: Soluble in ethanol, DMSO
- Intended Use: Research and forensic applications only
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