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5F-MDMB-2201 is a powerful indole-based synthetic cannabinoid with high affinity to CB1 receptors, making it ideal for binding studies, receptor mapping, toxicological profiling, and SAR analysis.

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πŸ§ͺ What is 5F-MDMB-2201?

5F-MDMB-2201 (5F-MDMB-PICA) is a potent synthetic cannabinoid belonging to the indole-3-carboxamide family. It acts as a full agonist at CB1 and CB2 receptors, and its structure includes a fluorinated pentyl side chain, which contributes to its strong binding efficacy and rapid metabolic breakdown.

➀ Chemical Profile:

  • IUPAC Name: Methyl (S)-2-[[1-(5-fluoropentyl)-1H-indole-3-carbonyl]amino]-3,3-dimethylbutanoate
  • Molecular Formula: C21H29FN2O3
  • Molar Mass: 376.5 g/mol
  • CAS Number: 1715016-75-3
  • Purity: β‰₯99%
  • Appearance: Off-white crystalline powder
  • Solubility: Soluble in ethanol, DMSO
  • Intended Use: For laboratory research only

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Every batch of 5F-MDMB-2201 is tested via HPLC to ensure β‰₯99% purity. Full COA and SDS documentation are available.

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🧬 Applications of 5F-MDMB-2201 in Research

This compound has been a breakthrough tool in several advanced research fields:

1. Cannabinoid Receptor Binding Assays

Used to study CB1 and CB2 receptor affinity, efficacy, and downstream signaling.

2. Forensic and Toxicology Studies

Serves as a reference material in forensic labs for synthetic cannabinoid detection in biological samples.

3. Pharmacokinetics and Metabolism

Helps map out metabolic pathways, half-life estimation, and enzyme interaction analysis.

4. SAR (Structure-Activity Relationship) Studies

Used to compare functional groups and binding efficiency within the synthetic cannabinoid class.

5. Analytical Instrument Calibration

Supports GC-MS and LC-MS profiling, as well as FTIR and NMR calibrations.


πŸ“‹ Technical Specifications of 5F-MDMB-2201

Feature Details
Product Name 5F-MDMB-2201
Chemical Class Indole-based synthetic cannabinoid
CAS Number 1715016-75-3
Molecular Formula C21H29FN2O3
Molecular Weight 376.5 g/mol
Purity β‰₯99% (HPLC Verified)
Appearance Crystalline white/off-white powder
Solubility Ethanol, Methanol, DMSO
Shelf Life 24 months (sealed, dry, room temp)
Shipping Global, stealth-packaged, tracked
Payment Methods BTC, ETH, USDT, Wire Transfer
Use Licensed lab research only

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❓ Frequently Asked Questions (FAQs)

1. Is it legal to buy 5F-MDMB-2201 online?

Legal status varies by country and region. You are responsible for checking the legal classification of 5F-MDMB-2201 in your location. BestChemsLab does not ship to banned jurisdictions.


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5. Do you offer bulk discounts or institutional supply contracts?

Yes. Orders of 10g, 50g, or 100g+ receive tiered discounts. We also support long-term supply agreements with academic, pharmaceutical, and forensic institutions.


⚠️ Legal & Safety Disclaimer

  • This compound is sold strictly for research purposes.
  • Not for human or veterinary consumption.
  • Purchasers are solely responsible for understanding and complying with local laws and regulations.
  • BestChemsLab assumes no liability for misuse.

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