Pregabalin Powder
$290.00 – $11,500.00
Pregabalin powder is a pharmaceutical‑grade active ingredient (API) in the form of a white crystalline powder (≥ 98 % purity), chemically known as (S)-3‑Aminomethyl‑5‑methylhexanoic acid (CAS 148553‑50‑8) . It’s used to manufacture Lyrica®️ and generic medications for treating neurological conditions.
Description
What Is Pregabalin Powder? | Definition & Overview
Pregabalin powder is a pharmaceutical‑grade active ingredient (API) in the form of a white crystalline powder (≥ 98 % purity), chemically known as (S)-3‑Aminomethyl‑5‑methylhexanoic acid (CAS 148553‑50‑8) . It’s used to manufacture Lyrica®️ and generic medications for treating neurological conditions.
Key Benefits & Uses of Pregabalin Powder
- Neuropathic Pain Relief: First-line treatment for diabetic peripheral neuropathy and postherpetic neuralgia; effective in fibromyalgia and central neuropathic pain .
- Seizure Control: Adjunct therapy for partial-onset seizures in adults .
- Generalized Anxiety Disorder (GAD): Clinically approved in the EU and other regions to relieve chronic anxiety .
- Off‑label Uses: May be used under supervision for restless legs syndrome, sleep disturbance, fibromyalgia-related fatigue, and even alcohol/benzodiazepine withdrawal .
Mechanism of Action – How Pregabalin Powder Works
Pregabalin binds specifically to the α₂δ‑1 subunit of voltage‑gated calcium channels in the central nervous system. By inhibiting excitatory neurotransmitter release (e.g., glutamate, norepinephrine), it reduces neuronal hyperactivity and dampens pain and seizure transmission .
Side Effects & Safety Profile
Common Side Effects
Includes dizziness, drowsiness, weight gain, blurred vision, peripheral edema, dry mouth and euphoria in a subset of users (> 1 %) .
Less Common but Serious Risks
Potential for angioedema, respiratory depression (especially with opioids or CNS depressants), kidney injury, and increased suicidal ideation? . Risk of dependence is low at therapeutic doses but can rise with misuse.
Special Precautions
- Use in pregnancy or breastfeeding is not fully established.
- Must follow regulated medical guidance and avoid illicit or unverified sources .
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FAQ Section
Q1: Is pregabalin powder soluble in water?
It’s sparingly soluble—only partial dissolution occurs, with fine particles or crystal fragments remaining undissolved in warm or room-temperature water, per user observations     .
Q2: Are generic/raw pregabalin powders reliable?
Quality varies. Some generic versions lack absorptive excipients like sodium lauryl sulfate, which may reduce effectiveness in certain individuals . Counterfeit product reports emphasize risks—non‑pharm standard sources are discouraged .
Q3: What purity grades are available?
Producers offer USP or EP standard powders with ≥ 98–99 % assay purity, compliant with Good Manufacturing Practices (GMP) and international pharmacopeias
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